Tailoring Exposure for Efficacy: Next Generation PK Optimization with KinetiSol-Enabled BAE and CR Design

Many drug candidates require more than solubility enhancement to achieve optimal therapeutic performance. This presentation from Dave Miller at CRBE Summit West (2026) explores how KinetiSol™ Technology can be used to tailor pharmacokinetic (PK) profiles through advanced amorphous solid dispersion (ASD) design.

Using a tetrabenazine case study, the presentation highlights how KinetiSol enabled a modified release formulation that reduced peak exposure while maintaining total drug exposure, supporting improved dosing flexibility and patient outcomes.