Solutions for Poorly Soluble Molecules
Problematic Drug Compounds
Approximately 70% of drugs in the development pipeline are considered to have either poor bioavailability, nonlinear pharmacokinetics, or a significant food effect on drug bioavailability due to poor solubility. Conventional formulation strategies may no longer provide acceptable in-vivo performance. The need to utilize advanced formulation technologies to overcome these issues is important.
AustinPx offers several technologies to improve the bioavailability of molecules:
- Amorphous Dispersions, including spray drying, HME and KinetiSol™ Technology
- Particle Size Reduction
- Lipid Delivery
- Complexation
- Fluid-bed Processing
- Hot-melt Granulations
- Micro-Precipitated Amorphous Powder (MAP)
AustinPx's team of scientists are expertly trained in applying bioavailability enhancement technologies to a range of molecules.
Screen Leading ASD Technologies Before You Choose
ASD technology selection can shape performance, timelines, scale-up risk, and long-term product value. Waiting too long to compare options can lock a program into a path that may not deliver the best result.
AustinPx helps teams evaluate Spray Drying (SD), Hot Melt Extrusion (HME), and KinetiSol™ Technology in one integrated ASD screening program. By screening all three leading technologies under one roof, we can help identify the right enabling formulation strategy faster, with less cost and complexity than managing multiple vendors.
Our approach supports:
- Rapid feasibility screening across SD, HME, and KinetiSol
- Prototype generation for animal PK testing
- Technology selection based on performance, manufacturability, and scalability
- Faster conversion from screening to development
- A clear path from early formulation decisions to clinical and commercial manufacturing
Rapid ASD Screening Program
Our rapid screening program is designed to help you compare technologies early, generate meaningful data quickly, and move forward with confidence. Whether your molecule needs improved exposure, a faster development path, or a scalable commercial option, AustinPx can help you determine the best ASD strategy before time and budget are spent on the wrong one.
Each drug candidate is unique, as is each Company. Our goal is to match the best enabling technology for clinical success with our your Company's corporate goals, timelines and budget. We work closely with you to develop a custom project plan tailored to their specific needs. This is combined with our client-centric service, collaborative communication, project management and scientific insights.
With a range of bioavailability enhancement technologies and GMP manufacturing capabilities to produce oral drug products, AustinPx can take you from clinical candidate to clinical trial material no matter what your solubility challenges may be.
Contact us today to learn how AustinPx can improve the solubility of your poorly soluble molecule.