Presentations
Redefining Drug-Like Properties with Kinetisol
Christopher Lipinski’s Rule of Five (Ro5) has been used for nearly three decades to evaluate whether a compound possesses the chemical and physical properties to potentially be an orally active drug in humans. But have modern molecules and technologies rendered Lipinski’s guidelines irrelevant?
The KinetiSol process accommodates high-temperature melters without issue and solvent solubility is irrelevant to the process. Compared to other technologies, KinetiSol formulations typically result in superior bioavailability, smoother planning and execution of manufacturing, and a significantly reduced environmental impact.